Nano rough micron patterned titanium for directing osteoblast morphology and adhesion

Nano rough micron patterned titanium for directing osteoblast morphology and adhesion

Previous studies have demonstrated greater functions ofosteoblasts (bone-forming cells) on nanophase compared with conventional metals. Nanophase metals possess a biologically inspired nanostructured surface that mimics the dimensions of constituent components in bone, including collagen and hydroxyapatite. Not only do these components possess dimensions on the nanoscale, they are aligned in a ...

Increased Osteoblast Adhesion on Nano-rough Anodized Titanium and CoCrMo

One approach to improve biological properties of current titanium and CoCrMo implant is to mimic the nanostructures of bone. Surface modification via anodization is popular to create such nanometer surface features on these metallic implants. The objective of the present study was to anodize titanium and CoCrMo and then determine osteoblast adhesion on such materials. Hydrofluoric acid was used...

Antibacterial titanium nano-patterned arrays inspired by dragonfly wings

Titanium and its alloys remain the most popular choice as a medical implant material because of its desirable properties. The successful osseointegration of titanium implants is, however, adversely affected by the presence of bacterial biofilms that can form on the surface, and hence methods for preventing the formation of surface biofilms have been the subject of intensive research over the pa...

Enhanced osteoblast adhesion to drug-coated anodized nanotubular titanium surfaces

Current orthopedic implants have functional lifetimes of only 10-15 years due to a variety of reasons including infection, extensive inflammation, and overall poor osseointegration (or a lack of prolonged bonding of the implant to juxtaposed bone). To improve properties of titanium for orthopedic applications, this study anodized and subsequently coated titanium with drugs known to reduce infec...

Discriminatory Bio-Adhesion Over Nano-Patterned Polymer Brushes